Dr. Peter Attia: Supplements for Longevity & Their Efficacy

In this episode of the Huberman Lab podcast, Dr. Andrew Huberman interviews Dr. Peter Attia, a physician specializing in longevity, to explore the efficacy of various supplements purported to extend lifespan.

They focus on the NAD pathway, discussing molecules like NAD, NMN, and NR, evaluating their roles in cellular energy production and DNA repair. Despite the theoretical benefits, Dr. Attia emphasizes that current human studies do not provide clear evidence that supplementing with these molecules effectively enhances healthspan or lifespan. He underscores the importance of critical thinking when considering such supplements, noting that many lack robust scientific justification.

Beyond supplements, the conversation highlights the significance of foundational lifestyle behaviors—such as regular physical activity, balanced nutrition, and adequate sleep—in promoting longevity. Dr. Attia suggests that these behavioral approaches play a more substantial role in extending healthspan compared to current supplementation strategies.

The episode also touches on the limitations of biological age tests and discusses factors like radiation exposure in relation to cancer risk. Overall, the dialogue encourages a cautious and evidence-based approach to supplements while prioritizing well-established lifestyle interventions for long-term health.